HitPredict

Interactor 1: RBM3 (P98179)
RNA-binding protein 3 (RNA-binding motif protein 3) (RNPL)
Gene: RBM3

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	26472337, 18427544, 29395067
Identification Methods	affinity chromatography technology, two hybrid, pull down, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045727 - positive regulation of translation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 326
+	Xl
		1092815 CIRBB_XENLA (3-157): 5.42e-34: 118: 55.00		ELV1A_XENLA (1-326): 7.61e-86: 263: 88.72
+	Hs
		1031344 PABP4_HUMAN (4-92): 2.48e-25: 102: 29.21		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		1020265 ELAV2_HUMAN (7-135): 2.08e-22: 93: 25.19		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Mm
		857310 TIA1_MOUSE (1-156): 1.99e-21: 90.7: 18.63		ELAV1_MOUSE (1-326): 3.74e-90: 274: 98.47
+	Hs
		963526 TIAR_HUMAN (1-153): 9.59e-22: 91.4: 17.42		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		680455 TIA1_HUMAN (1-156): 2.56e-21: 90.3: 18.63		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Mm
		936687 Q80ZW7_MOUSE (1-94): 2.81e-19: 84.5: 26.32		ELAV1_MOUSE (1-326): 3.74e-90: 274: 98.47
+	Hs
		1020259 ELAV2_HUMAN (7-135): 2.08e-22: 93: 25.19		ELAV3_HUMAN (1-326): 4.41e-84: 259: 62.82
+	Hs
		958182 RBM3_HUMAN (1-157): 1.14e-38: 130: 100.00		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		1020353 PPIE_HUMAN (1-94): 1.48e-31: 116: 34.04		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516744 PPIE_HUMAN (1-94): 1.48e-31: 116: 34.04		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		1020249 PABP4_HUMAN (4-92): 2.48e-25: 102: 29.21		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516495 PABP4_HUMAN (4-92): 2.48e-25: 102: 29.21		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		516484 ELAV2_HUMAN (7-135): 2.08e-22: 93: 25.19		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		516471 TIAR_HUMAN (1-153): 9.59e-22: 91.4: 17.42		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Mm
		665745 TIA1_MOUSE (1-156): 1.99e-21: 90.7: 18.63		PABP1_MOUSE (234-325): 2.2e-20: 93.5: 19.57
+	Hs
		474021 PABP4_HUMAN (4-92): 2.48e-25: 102: 29.21		PAB4L_HUMAN (20-184): 3.03e-12: 68.6: 28.42
+	Hs
		474019 ELAV2_HUMAN (7-135): 2.08e-22: 93: 25.19		PAB4L_HUMAN (20-184): 3.03e-12: 68.6: 28.42