HitPredict

Interactor 1: AT2C1 (P98194)
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1)
Gene: ATP2C1

Interactor 2: GPR35 (Q9HC97)
G-protein coupled receptor 35 (Kynurenic acid receptor) (KYNA receptor)
Gene: GPR35

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 919 Hs			1 309
+	Hs
		849663 AT2C1_HUMAN (1-919): 0: 865: 100.00		CCR6_HUMAN (14-309): 6.89e-75: 235: 23.10
+	Hs
		666305 AT2C1_HUMAN (1-919): 0: 865: 100.00		NK3R_HUMAN (7-294): 1.51e-60: 201: 18.89
+	Hs
		530845 AT1A3_HUMAN (10-905): 0: 801: 25.86		P2RY2_HUMAN (1-297): 1.05e-78: 245: 27.53
+	Hs
		530883 AT1A3_HUMAN (10-905): 0: 801: 25.86		GPR17_HUMAN (4-292): 6.71e-78: 243: 27.82
+	Hs
		782452 AT2A3_HUMAN (24-903): 0: 785: 31.72		P2RY2_HUMAN (1-297): 1.05e-78: 245: 27.53
+	Hs
		1031036 AT2A3_HUMAN (24-903): 0: 785: 31.72		GPR17_HUMAN (4-292): 6.71e-78: 243: 27.82
+	Hs
		393358 AT1A1_HUMAN (14-905): 0: 805: 26.16		GPR35_HUMAN (1-309): 5.97e-71: 223: 100.00
+	Hs
		530977 AT1A3_HUMAN (10-905): 0: 801: 25.86		GPR35_HUMAN (1-309): 5.97e-71: 223: 100.00
+	Hs
		392982 AT1A1_HUMAN (14-905): 0: 805: 26.16		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		849697 AT2A3_HUMAN (24-903): 0: 785: 31.72		CCR6_HUMAN (14-309): 6.89e-75: 235: 23.10
+	Hs
		530844 AT1A3_HUMAN (10-905): 0: 801: 25.86		OPRX_HUMAN (2-306): 3.38e-64: 208: 24.06
+	Hs
		1274531 AT2A3_HUMAN (24-903): 0: 785: 31.72		GPR35_HUMAN (1-309): 5.97e-71: 223: 100.00
+	Hs
		530839 AT1A3_HUMAN (10-905): 0: 801: 25.86		NK3R_HUMAN (7-294): 1.51e-60: 201: 18.89
+	Hs
		530862 AT1A3_HUMAN (10-905): 0: 801: 25.86		CXCR4_HUMAN (8-299): 1.12e-60: 198: 20.26
+	Hs
		428908 AT2A2_HUMAN (24-915): 0: 762: 32.01		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		561517 AT2A2_HUMAN (24-915): 0: 762: 32.01		OPRD_HUMAN (15-305): 1.16e-63: 206: 22.55
+	Hs
		561533 AT2A2_HUMAN (24-915): 0: 762: 32.01		CCR4_HUMAN (9-295): 1.33e-62: 203: 20.53
+	Hs
		531008 AT1A3_HUMAN (10-905): 0: 801: 25.86		GPR55_HUMAN (48-284): 1.07e-33: 127: 36.03
+	Hs
		530835 AT1A3_HUMAN (10-905): 0: 801: 25.86		PTAFR_HUMAN (29-285): 9.99e-26: 106: 27.21
+	Hs
		393214 AT1A1_HUMAN (14-905): 0: 805: 26.16		P2RY6_HUMAN (30-284): 1.38e-19: 89.4: 30.29