HitPredict

Interactor 1: KGD (P9WIS5)
Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
Gene: KGD

Interactor 2: GARA (P9WJA9)
Glycogen accumulation regulator GarA
Gene: GARA

Species: Mycobacterium tuberculosis H37Rv

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.830

Property	Details
Experiments	19019160, 19318624
Identification Methods	pull down, surface plasmon resonance
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	E1_dh~FHA
Common GO terms	GO:0005886 - plasma membrane GO:0009274 - peptidoglycan-based cell wall
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1231 Mt			1 162
+	Ms
		49517 KGD_MYCS2 (1-1231): 0: 1510: 84.73		GARA_MYCS2 (1-160): 3.1e-95: 273: 84.38