HitPredict

Interactor 1: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 726
+	Hs
		1067153 HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		175778 HMGB3_HUMAN (46-136): 1.77e-17: 79.8: 21.98		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		959092 TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		959090 TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00		BRPF3_HUMAN (37-484): 7.42e-31: 132: 14.82
+	Hs
		1342352 HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		244288 TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		999037 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		225734 SOX15_HUMAN (115-231): 7.87e-21: 89.4: 15.70		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		989526 SOX4_HUMAN (148-229): 1.28e-18: 86: 22.09		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		643336 HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		449701 HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		1311924 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		CECR2_HUMAN (134-594): 1.39e-24: 112: 14.23
+	Hs
		244970 HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		1199188 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		1199196 SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		225755 SOX15_HUMAN (115-231): 7.87e-21: 89.4: 15.70		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		989539 SOX4_HUMAN (148-229): 1.28e-18: 86: 22.09		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		175732 HMGB3_HUMAN (46-136): 1.77e-17: 79.8: 21.98		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		243964 HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		243829 HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56