HitPredict

Interactor 1: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1235
+	Hs
		959086 TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00		BAZ2A_HUMAN (125-815): 2.72e-30: 132: 10.85
+	Hs
		1311941 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		TRI33_HUMAN (820-1232): 7.65e-33: 140: 11.56
+	Hs
		1332331 SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29		TRI33_HUMAN (820-1232): 7.65e-33: 140: 11.56
+	Hs
		170279 SOX5_HUMAN (49-150): 1.14e-23: 101: 12.75		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		170464 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		170476 SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		1311932 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		1332323 SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		999037 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		225734 SOX15_HUMAN (115-231): 7.87e-21: 89.4: 15.70		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		989526 SOX4_HUMAN (148-229): 1.28e-18: 86: 22.09		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		1199188 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		1199196 SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		225755 SOX15_HUMAN (115-231): 7.87e-21: 89.4: 15.70		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		989539 SOX4_HUMAN (148-229): 1.28e-18: 86: 22.09		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		847069 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Dm
		116021 Q9VUD3_DROME (144-228): 1.27e-24: 103: 20.23		M9PH39_DROME (622-802): 6.14e-14: 79.5: 23.28
+	Hs
		846943 SOX4_HUMAN (148-229): 1.28e-18: 86: 22.09		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		1270803 HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22
+	Hs
		1270781 SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22