HitPredict

Interactor 1: VIGLN (Q00341)
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)
Gene: HDLBP

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36244648
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1268 Hs			1 482
+	Hs
		959391 VIGLN_HUMAN (1-1268): 0: 939: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1294278 FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1283866 FUBP1_HUMAN (641-950): 1.47e-27: 121: 14.21		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		128341 IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1349171 IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030422 FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		128164 IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030522 IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Sc
		410434 SC160_YEAST (541-1201): 1.71e-29: 130: 14.22		BRE5_YEAST (9-419): 2.98e-56: 197: 15.59
+	Hs
		1073540 FUBP1_HUMAN (641-950): 1.47e-27: 121: 14.21		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		1272077 FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		311352 FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85		CELF2_HUMAN (309-419): 2e-14: 77.2: 18.10
+	Hs
		1272070 FUBP2_HUMAN (227-575): 5.22e-28: 123: 13.06		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272071 FUBP1_HUMAN (641-950): 1.47e-27: 121: 14.21		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		884351 PCBP3_HUMAN (934-1148): 1.25e-24: 109: 18.27		CELF4_HUMAN (288-416): 2.41e-16: 83.4: 16.67
+	Hs
		128256 IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1072148 PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272119 IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272097 BICC1_HUMAN (452-812): 8.1e-20: 98: 17.05		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		311358 IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52		CELF2_HUMAN (309-419): 2e-14: 77.2: 18.10