HitPredict

Interactor 1: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 305 Hs			1 246
+	Hs
		909447 CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		625306 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		625296 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		625383 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		909449 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904447 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		841128 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		960433 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		683268 CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646799 CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		625334 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		625130 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683964 CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		926925 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683270 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		414774 CDK1_HUMAN (1-290): 1.16e-137: 392: 65.98		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		646801 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683213 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646734 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683966 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20