HitPredict

Interactor 1: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 582
+	Hs
		625477 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		414946 CDK1_HUMAN (1-290): 1.16e-137: 392: 65.98		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960291 CDK5_HUMAN (1-292): 8.97e-133: 380: 60.75		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960440 CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960373 CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403088 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	At
		1103363 CKB12_ARATH (1-292): 1.59e-131: 377: 56.77		LRP1A_ARATH (10-367): 4.77e-56: 204: 16.85
+	Hs
		516362 CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Sc
		565522 PHO85_YEAST (3-290): 9.48e-130: 373: 54.21		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Hs
		841320 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Sc
		339316 CDK1_YEAST (3-288): 1.32e-131: 377: 63.92		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Dm
		582590 CDK2_DROME (1-301): 6.29e-129: 371: 60.47		SXL_DROME (59-259): 1.13e-24: 107: 20.29
+	Hs
		841335 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		414931 CDK1_HUMAN (1-290): 1.16e-137: 392: 65.98		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	At
		1321248 CDKD2_ARATH (1-302): 9.62e-128: 369: 48.01		PABP8_ARATH (2-127): 5.76e-15: 80: 11.91
+	Hs
		841210 CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50