HitPredict

Interactor 1: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Interactor 2: C2CD5 (Q86YS7)
C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa)
Gene: C2CD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	25852190, 26186194, 28514442, 33961781, 32707033, 36736316, 23602568, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0090314 - positive regulation of protein targeting to membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 292 Hs			1 1000
+	Hs
		625506 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		625586 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Mm
		829603 CDK5_MOUSE (1-292): 9.13e-139: 394: 99.66		ESYT1_MOUSE (12-114): 1.49e-11: 70.9: 22.73