HitPredict

Interactor 1: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007283 - spermatogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 582
+	Hs
		960440 CDK17_HUMAN (4-490): 2.31e-154: 451: 68.67		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		625477 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960098 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		989681 CDK18_HUMAN (1-490): 5.61e-137: 405: 61.84		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		414946 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116470 CDK15_HUMAN (79-488): 6.12e-133: 393: 46.01		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		300640 CDK14_HUMAN (159-474): 3.24e-130: 387: 60.19		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		960291 CDK5_HUMAN (162-452): 9.2e-133: 387: 55.97		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403088 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		516362 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		989704 CDK18_HUMAN (1-490): 5.61e-137: 405: 61.84		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Sc
		565522 PHO85_YEAST (163-451): 5.83e-132: 386: 53.36		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Hs
		841320 CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Sc
		339316 CDK1_YEAST (160-448): 1.21e-128: 377: 50.68		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		841335 CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Dm
		582590 CDK2_DROME (162-460): 6.51e-129: 378: 45.52		SXL_DROME (59-259): 1.13e-24: 107: 20.29
+	Dm
		114975 M9PE01_DROME (4-479): 2.66e-136: 405: 43.81		LARP_DROME (38-120): 1.58e-13: 76.1: 35.23
+	Hs
		414931 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		841210 CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50