HitPredict

Interactor 1: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Interactor 2: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 1253
+	Hs
		625176 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		522604 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH7_HUMAN (150-1188): 3.75e-36: 152: 9.38
+	Hs
		528401 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		MYH8_HUMAN (204-1091): 5.47e-30: 132: 8.85
+	Hs
		522542 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH1_HUMAN (218-1028): 1.17e-30: 133: 8.58
+	Hs
		528405 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH8_HUMAN (204-1091): 5.47e-30: 132: 8.85
+	Hs
		724717 CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		502908 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH3_HUMAN (195-1037): 5.65e-25: 115: 10.75
+	Hs
		625177 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92
+	Hs
		960128 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH2_HUMAN (209-846): 1.47e-18: 94.3: 9.13
+	Hs
		148286 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		CTRO_HUMAN (529-1124): 1.75e-19: 97.5: 10.68
+	Hs
		528368 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH6_HUMAN (190-713): 6.05e-13: 76.2: 10.19
+	Hs
		725114 CDK7_HUMAN (160-481): 5.55e-132: 387: 37.69		MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92
+	Hs
		625446 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17
+	Hs
		551610 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		960129 CDK3_HUMAN (162-453): 2.39e-142: 412: 53.06		MYH13_HUMAN (541-1107): 4.64e-09: 63.4: 15.67
+	Hs
		415051 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		SCAPE_HUMAN (381-807): 4.43e-11: 70: 19.56
+	Hs
		414713 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		551810 CDK15_HUMAN (79-488): 6.12e-133: 393: 46.01		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03