HitPredict

Interactor 1: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Interactor 2: CCNY (Q8ND76)
Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X)
Gene: CCNY

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 28514442, 33961781, 32707033, 22184064
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay, two hybrid, pull down
Interaction Type physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_N~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007283 - spermatogenesis
GO:0010508 - positive regulation of autophagy
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 496
Hs

1 341
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Ce
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024