HitPredict

Interactor 1: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 779
+	Hs
		625600 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		415064 CDK1_HUMAN (162-451): 2.98e-136: 397: 51.88		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		960330 CDK5_HUMAN (162-452): 9.2e-133: 387: 55.97		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		960382 CDK16_HUMAN (1-496): 2.61e-178: 511: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		960360 CDK16_HUMAN (1-496): 2.61e-178: 511: 100.00		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		960375 CDK16_HUMAN (1-496): 2.61e-178: 511: 100.00		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		960413 CDK16_HUMAN (1-496): 2.61e-178: 511: 100.00		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		625526 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		CNKR2_HUMAN (1-468): 1.39e-46: 181: 13.77
+	Hs
		625495 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		625491 CDK2_HUMAN (162-456): 6.05e-145: 418: 53.54		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81