HitPredict

Interactor 1: NAM8 (Q00539)
Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8)
Gene: NAM8

Interactor 2: NCBP2 (Q08920)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: CBC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.943

Property	Details
Experiments	11805826, 24500206, 24476359, 16429126, 37968396, 21558325
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000243 - commitment complex GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 523 Sc			1 208
+	Sc
		960486 NAM8_YEAST (1-523): 7.39e-89: 284: 100.00		HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75
+	Sc
		376958 PABP_YEAST (3-323): 4.49e-41: 157: 12.87		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00
+	Hs
		853881 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Hs
		516425 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Hs
		1020249 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		ELAV2_HUMAN (4-155): 3.36e-22: 94.3: 16.13
+	Sp
		145447 PABP_SCHPO (3-339): 1.87e-41: 159: 12.83		PAB2_SCHPO (35-119): 7.62e-28: 104: 30.59
+	Hs
		516495 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		PABP1_HUMAN (47-175): 1.75e-20: 90.5: 14.60
+	Hs
		516484 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		ELAV2_HUMAN (4-155): 3.36e-22: 94.3: 16.13
+	Zm
		8143 A0A1D6ELH4_MAIZE (3-457): 7.87e-36: 143: 11.93		A0A1D6ELH4_MAIZE (44-175): 1.07e-20: 91.3: 17.91
+	Hs
		516339 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		PABP1_HUMAN (47-175): 1.75e-20: 90.5: 14.60
+	Mm
		665745 PABP1_MOUSE (153-523): 8.37e-36: 143: 13.78		TIA1_MOUSE (41-180): 1.95e-20: 89.7: 20.00
+	Hs
		516689 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		PABP3_HUMAN (47-175): 2.53e-19: 87.4: 15.33
+	Sc
		376663 PABP_YEAST (3-323): 4.49e-41: 157: 12.87		NSR1_YEAST (34-143): 2.23e-14: 72.8: 20.91
+	Hs
		516471 TIAR_HUMAN (3-312): 6.51e-29: 119: 14.60		PABP1_HUMAN (47-175): 1.75e-20: 90.5: 14.60
+	Hs
		680422 TIA1_HUMAN (3-329): 4.37e-29: 120: 13.45		TIA1_HUMAN (41-180): 2.11e-20: 89.3: 20.00
+	Hs
		680439 TIAR_HUMAN (3-312): 6.51e-29: 119: 14.60		TIA1_HUMAN (41-180): 2.11e-20: 89.3: 20.00