Interactor 1: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st
Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.27 | 1.00 | 0.527 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23454976 |
| Identification Methods | unspecified method |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~fn3, SH2~fn3 |
| Common GO terms | GO:0007165 - signal transduction GO:0008284 - positive regulation of cell population proliferation GO:0019221 - cytokine-mediated signaling pathway GO:0042102 - positive regulation of T cell proliferation GO:0042531 - positive regulation of tyrosine phosphorylation of STAT protein and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
