HitPredict

Interactor 1: PURA (Q00577)
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Gene: PURA

Interactor 2: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 272
+	Hs
		960501 PURA_HUMAN (1-322): 1.72e-144: 411: 100.00		SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64
+	Hs
		960505 PURA_HUMAN (1-322): 1.72e-144: 411: 100.00		SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96
+	Hs
		1028865 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00
+	Mm
		788752 PURA_MOUSE (1-322): 5.38e-143: 408: 98.76		TIA1_MOUSE (2-101): 7.98e-13: 69.3: 15.69
+	Hs
		951925 PURA_HUMAN (1-322): 1.72e-144: 411: 100.00		SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56
+	Hs
		1031491 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98
+	Hs
		474041 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		PAB4L_HUMAN (5-75): 5.48e-14: 72.8: 24.68