HitPredict

Interactor 1: PURA (Q00577)
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Gene: PURA

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29845934, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 582
+	Hs
		1116471 PURB_HUMAN (52-290): 5.82e-111: 326: 72.29		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116611 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Mm
		788752 PURA_MOUSE (1-322): 5.38e-143: 408: 98.76		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		1031491 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		474041 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		1347045 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		1162709 PURG_HUMAN (51-301): 2.2e-105: 313: 53.22		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23