Interactor 1: RAD25 (Q00578)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 (TFIIH subunit XPB/SSL2) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB/SSL2) (DNA repair helicase RAD25/SSL2) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
Gene: SSL2

Interactor 2: TFB2 (Q02939)
General transcription and DNA repair factor IIH subunit TFB2 (TFIIH subunit TFB2) (RNA polymerase II transcription factor B 52 kDa subunit) (RNA polymerase II transcription factor B p52 subunit) (RNA polymerase II transcription factor B subunit 2)
Gene: TFB2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 10681587, 26340423, 19897425, 36041630, 37968396
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC3_RAD25_C~Tfb2, ERCC3_RAD25_C~Tfb2_C, Helicase_C_3~Tfb2
Common GO terms GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 843
Sc

1 513
+ Hs
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024