Interactor 1: RAD25 (Q00578)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 (TFIIH subunit XPB/SSL2) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB/SSL2) (DNA repair helicase RAD25/SSL2) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
Gene: SSL2

Interactor 2: TFB3 (Q03290)
RNA polymerase II transcription factor B subunit 3 (RNA polymerase II transcription factor B 38 kDa subunit) (RNA polymerase II transcription factor B p38 subunit)
Gene: TFB3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 26340423, 19818408, 37968396, 22308316, 22411836
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, biochemical
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C_3~MAT1
Common GO terms GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 843
Sc

1 321
+ Hs

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Last updated: 15 Jul 2024