HitPredict

Interactor 1: RAD25 (Q00578)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 (TFIIH subunit XPB/SSL2) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB/SSL2) (DNA repair helicase RAD25/SSL2) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
Gene: SSL2

Interactor 2: TFB4 (Q12004)
General transcription and DNA repair factor IIH subunit TFB4 (TFIIH subunit TFB4) (RNA polymerase II transcription factor B 34 kDa subunit) (RNA polymerase II transcription factor B p34 subunit) (RNA polymerase II transcription factor B subunit 4)
Gene: TFB4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.680

The method score is based on:

Property Details
Experiments 10681587, 19818408, 37968396, 26340423
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 843
Sc

1 338
+ Hs

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Last updated: 15 Jul 2024