HitPredict

Interactor 1: BORG5 (Q00587)
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
Gene: CDC42EP1

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 258
+	Hs
		436256 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		960645 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66
+	Hs
		892320 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		950927 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		925198 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		900382 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545325 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		893907 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564481 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		960657 BORG5_HUMAN (1-391): 1.77e-158: 452: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26
+	Hs
		1296733 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66
+	Hs
		1183550 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00
+	Hs
		892591 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		951333 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		925610 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		900891 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545611 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		894420 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564682 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		1330288 BORG4_HUMAN (25-280): 3.94e-67: 218: 30.54		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26