Interactor 1: CD80 (Q00609)
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (B7) (CD antigen CD80)
Gene: CD80

Interactor 2: PD1L1 (Q9EP73)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: Cd274

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 23417675, 31000591, 21884581
Identification Methods surface plasmon resonance, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~V-set, V-set~V-set
Common GO terms GO:0006955 - immune response
GO:0007166 - cell surface receptor signaling pathway
GO:0009897 - external side of plasma membrane
GO:0009986 - cell surface
GO:0031295 - T cell costimulation
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 306
Mm

1 290
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024