HitPredict

Interactor 1: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Interactor 2: TM1L2 (Q6ZVM7)
TOM1-like protein 2 (Target of Myb-like protein 2)
Gene: TOM1L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16412388
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0016020 - membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1675 Hs			1 507
+	Hs
		241163 CLH1_HUMAN (1-1675): 0: 3132: 100.00		TOM1_HUMAN (1-507): 1.07e-155: 454: 61.40
+	Hs
		961012 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GGA2_HUMAN (5-477): 1.27e-101: 319: 21.15
+	Hs
		272801 CLH1_HUMAN (1-1675): 0: 3132: 100.00		TM1L1_HUMAN (7-468): 4.22e-95: 298: 29.90
+	Hs
		961013 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GGA1_HUMAN (13-474): 5.55e-93: 297: 22.74
+	Hs
		960908 CLH1_HUMAN (1-1675): 0: 3132: 100.00		STAM1_HUMAN (1-491): 2.46e-92: 293: 19.80
+	Hs
		960999 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GGA3_HUMAN (12-497): 1.56e-90: 293: 20.36
+	Mm
		1148410 CLH1_MOUSE (1-1675): 0: 3131: 99.88		TM1L1_MOUSE (7-474): 9.35e-90: 284: 29.92
+	Hs
		241158 CLH2_HUMAN (1-1634): 0: 2869: 85.01		TOM1_HUMAN (1-507): 1.07e-155: 454: 61.40
+	Hs
		159961 CLH1_HUMAN (1-1675): 0: 3132: 100.00		HGS_HUMAN (13-166): 1.32e-41: 160: 33.55
+	Mm
		1148412 CLH1_MOUSE (1-1675): 0: 3131: 99.88		HGS_MOUSE (13-166): 5.07e-41: 159: 33.55
+	Hs
		863981 CLH2_HUMAN (1-1634): 0: 2869: 85.01		STAM1_HUMAN (1-491): 2.46e-92: 293: 19.80
+	Dm
		669650 CLH_DROME (1-1663): 0: 2911: 80.17		Q9W329_DROME (10-440): 1.82e-59: 209: 15.39
+	Dm
		669603 CLH_DROME (1-1663): 0: 2911: 80.17		HRS_DROME (9-167): 1.95e-40: 157: 34.36
+	Ce
		712329 CLH_CAEEL (5-1671): 0: 2799: 71.19		Q17796_CAEEL (10-400): 2.19e-69: 237: 16.98
+	Zm
		25357 A0A1D6IQ85_MAIZE (6-1617): 0: 2658: 56.96		C4J1G1_MAIZE (11-505): 1.85e-82: 268: 25.40
+	Sc
		604476 CLH_YEAST (5-1648): 0: 2443: 49.79		GGA1_YEAST (10-429): 2.68e-71: 238: 18.65
+	Sc
		604404 CLH_YEAST (5-1648): 0: 2443: 49.79		GGA2_YEAST (11-378): 1.03e-68: 232: 21.80