HitPredict

Interactor 1: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Interactor 2: EHD4 (Q9H223)
EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4)
Gene: EHD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030132 - clathrin coat of coated pit GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1675 Hs			1 541
+	Hs
		960975 CLH1_HUMAN (1-1675): 0: 3132: 100.00		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Dm
		669597 CLH_DROME (1-1663): 0: 2911: 80.17		Q8T8W3_DROME (8-534): 0: 778: 65.54
+	Hs
		960921 CLH1_HUMAN (1-1675): 0: 3132: 100.00		REPS1_HUMAN (391-530): 2.28e-35: 143: 30.50
+	Hs
		960815 CLH1_HUMAN (1-1675): 0: 3132: 100.00		ITSN1_HUMAN (428-540): 3.64e-30: 128: 36.28
+	Hs
		787895 CLH1_HUMAN (1-1675): 0: 3132: 100.00		EPS15_HUMAN (449-532): 1.75e-12: 72.3: 35.29
+	Dm
		112571 CLH_DROME (1-1663): 0: 2911: 80.17		M9ND00_DROME (435-535): 1.96e-10: 65.9: 37.86