HitPredict

Interactor 1: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Interactor 2: MLP3A (Q9H492)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)
Gene: MAP1LC3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	24067654, 20562859, 22963397
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1675 Hs			1 121
+	Hs
		891083 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		306111 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		960958 CLH1_HUMAN (1-1675): 0: 3132: 100.00		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		960963 CLH1_HUMAN (1-1675): 0: 3132: 100.00		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Rn
		509762 CLH1_RAT (1-1675): 0: 3123: 99.76		GBRAP_RAT (7-121): 2.99e-52: 161: 30.44
+	Hs
		864008 CLH2_HUMAN (1-1634): 0: 2869: 85.01		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		863920 CLH2_HUMAN (1-1634): 0: 2869: 85.01		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		306041 CLH2_HUMAN (1-1634): 0: 2869: 85.01		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		864003 CLH2_HUMAN (1-1634): 0: 2869: 85.01		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		864005 CLH2_HUMAN (1-1634): 0: 2869: 85.01		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Sc
		604395 CLH_YEAST (5-1648): 0: 2443: 49.79		ATG8_YEAST (3-120): 2.38e-54: 167: 35.59