HitPredict

Interactor 1: MGN (P61326)
Protein mago nashi homolog
Gene: MAGOH

Interactor 2: THOC4 (Q86V81)
THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF)
Gene: ALYREF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

The method score is based on:

Property	Details
Experiments	39358380, 23084401, 37020021
Identification Methods	cross-linking study, affinity chromatography technology, pull down
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Mago_nashi~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006406 - mRNA export from nucleus and 3 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	146
Hs

1	257

Service provided by Combinatics, Japan

Last updated: 11Aug2025