HitPredict

Interactor 1: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Interactor 2: Q53FA3 (Q53FA3)
Heat shock 70 kDa protein 1-like
Gene: HSPA1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27173435
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 641
+	Hs
		713944 HSF1_HUMAN (1-529): 0: 610: 100.00		HS71L_HUMAN (1-641): 0: 979: 99.69
+	Hs
		503905 HSF1_HUMAN (1-529): 0: 610: 100.00		HSP7C_HUMAN (4-615): 0: 942: 84.64
+	Hs
		871531 HSF1_HUMAN (1-529): 0: 610: 100.00		HSP72_HUMAN (3-641): 0: 930: 81.59
+	Mm
		750734 HSF1_MOUSE (1-529): 0: 587: 89.23		HS71A_MOUSE (4-641): 0: 942: 87.34
+	Hs
		503937 HSF2_HUMAN (12-480): 5.68e-135: 403: 37.87		HSP7C_HUMAN (4-615): 0: 942: 84.64
+	Hs
		871535 HSF2_HUMAN (12-480): 5.68e-135: 403: 37.87		HSP72_HUMAN (3-641): 0: 930: 81.59
+	Dm
		611941 HSF_DROME (6-453): 1.06e-97: 312: 32.35		HSP73_DROME (8-641): 0: 941: 73.80
+	At
		612298 HFA1A_ARATH (15-445): 7.75e-90: 286: 22.12		HS701_ARATH (3-641): 0: 935: 73.15
+	At
		781120 HFA1A_ARATH (15-445): 7.75e-90: 286: 22.12		HS704_ARATH (3-641): 0: 934: 73.77
+	Hs
		1120591 Q9HAV2_HUMAN (371-529): 3.92e-65: 210: 99.37		Q53FC7_HUMAN (1-641): 0: 947: 78.69
+	Hs
		871792 Q9HAV2_HUMAN (371-529): 3.92e-65: 210: 99.37		HSP72_HUMAN (3-641): 0: 930: 81.59