HitPredict

Interactor 1: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Interactor 2: SMC6 (Q96SB8)
Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (hSMC6)
Gene: SMC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27173435, 35906200
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body GO:0097431 - mitotic spindle pole
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 1091
+	Hs
		961286 HSF1_HUMAN (1-529): 0: 610: 100.00		SMC4_HUMAN (2-977): 1e-39: 162: 10.55
+	Hs
		551668 HSF1_HUMAN (1-529): 0: 610: 100.00		DESP_HUMAN (126-744): 7.41e-23: 108: 8.27