HitPredict

Interactor 1: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.702

The method score is based on:

Property Details
Experiments 16293251, 23344957, 36339263, 14532117
Identification Methods affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000165 - MAPK cascade
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 529
Hs

1 303
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024