HitPredict

Interactor 1: NFKB2 (Q00653)
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
Gene: NFKB2

Interactor 2: TNIP2 (Q8NFZ5)
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
Gene: TNIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	27609421, 14743216
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 900 Hs			1 429
+	Mm
		638467 NFKB1_MOUSE (6-881): 0: 603: 41.91		TNIP2_MOUSE (2-429): 0: 639: 79.21
+	Hs
		587640 NFKB1_HUMAN (6-881): 0: 586: 41.27		TNIP2_HUMAN (1-429): 0: 648: 100.00
+	Hs
		981649 REL_HUMAN (33-456): 2.67e-112: 359: 33.88		TNIP2_HUMAN (1-429): 0: 648: 100.00
+	Hs
		978816 TF65_HUMAN (24-354): 9.91e-113: 358: 40.96		TNIP2_HUMAN (1-429): 0: 648: 100.00
+	Hs
		964503 RELB_HUMAN (27-356): 5.22e-89: 296: 39.34		TNIP2_HUMAN (1-429): 0: 648: 100.00