HitPredict

Interactor 1: SDHA (Q00711)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (FP)
Gene: SDH1

Interactor 2: SDHF2 (Q08230)
Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2)
Gene: SDH5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	19628817, 32051233, 23043141
Identification Methods	tandem affinity purification, cross-linking study, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FAD_binding_2~Sdh5, Sdh5~Succ_DH_flav_C
Common GO terms	GO:0005739 - mitochondrion GO:0006099 - tricarboxylic acid cycle GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 640 Sc			1 162
+	Hs
		678094 SDHA_HUMAN (1-640): 0: 924: 63.49		SDHF2_HUMAN (33-158): 5.76e-45: 146: 43.94