HitPredict

Interactor 1: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Interactor 2: RETR3 (Q86VR2)
Reticulophagy regulator 3
Gene: RETREG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071782 - endoplasmic reticulum tubular network
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 466
+	Hs
		1202349 REEP6_HUMAN (4-177): 7.33e-77: 230: 58.05		RETR3_HUMAN (1-466): 0: 726: 100.00
+	Hs
		1202385 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		RETR3_HUMAN (1-466): 0: 726: 100.00
+	Hs
		961826 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		RETR1_HUMAN (42-459): 0: 584: 36.82
+	Hs
		961736 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		RETR2_HUMAN (46-459): 1.23e-172: 497: 34.14