HitPredict

Interactor 1: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Interactor 2: REEP4 (Q9H6H4)
Receptor expression-enhancing protein 4
Gene: REEP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0071782 - endoplasmic reticulum tubular network
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 257
+	Hs
		961800 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Hs
		961828 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		REEP1_HUMAN (1-160): 4.17e-71: 218: 73.13
+	Hs
		961778 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		REEP6_HUMAN (1-181): 2.42e-61: 193: 25.28
+	Mm
		1321721 Q9CQG4_MOUSE (5-189): 7.84e-87: 254: 93.51		Q9CQG4_MOUSE (1-125): 1.33e-58: 185: 34.92
+	Hs
		1156242 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		1156238 REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		1293750 REEP6_HUMAN (4-177): 7.33e-77: 230: 58.05		REEP6_HUMAN (1-181): 2.42e-61: 193: 25.28
+	Hs
		1310089 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Hs
		1156243 REEP1_HUMAN (54-176): 7.91e-46: 151: 34.15		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		1332291 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		REEP1_HUMAN (1-160): 4.17e-71: 218: 73.13
+	Hs
		1310090 REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15		REEP1_HUMAN (1-160): 4.17e-71: 218: 73.13
+	Dm
		54455 A1Z9M2_DROME (4-163): 1.81e-68: 208: 47.83		A1Z9M2_DROME (1-114): 1.76e-52: 170: 26.96
+	At
		1209447 HA22J_ARATH (49-184): 1.47e-45: 152: 23.91		HA22J_ARATH (1-225): 2.03e-68: 213: 26.88
+	Dm
		94590 F2FB55_DROME (32-163): 1.93e-57: 179: 52.27		F2FB55_DROME (1-114): 1e-52: 170: 26.96