HitPredict

Interactor 1: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 249
+	Hs
		310604 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310816 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		961743 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Dm
		1177130 Q7JRH2_DROME (49-184): 1.05e-50: 166: 28.68		Q9W4N8_DROME (15-216): 1.28e-52: 173: 37.56
+	Sc
		767989 YOP1_YEAST (11-178): 1.99e-42: 142: 33.92		SCS2_YEAST (16-172): 2.69e-32: 119: 26.79