HitPredict

Interactor 1: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Interactor 2: PRAF1 (Q9UI14)
Prenylated Rab acceptor protein 1 (PRA1 family protein 1)
Gene: RABAC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	28514442, 33961781, 35271311, 21900206
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 185
+	Hs
		277693 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		PRAF3_HUMAN (39-185): 1.57e-39: 134: 21.85
+	Hs
		242243 REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13
+	Hs
		1310096 REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Dm
		52861 A1Z9M2_DROME (4-163): 1.81e-68: 208: 47.83		A1Z823_DROME (22-181): 2.02e-40: 137: 32.50
+	Dm
		52864 F2FB55_DROME (32-163): 1.93e-57: 179: 52.27		A1Z823_DROME (22-181): 2.02e-40: 137: 32.50
+	Mm
		1247007 REEP3_MOUSE (54-176): 4.15e-45: 151: 29.27		PRAF3_MOUSE (39-185): 1.01e-38: 132: 21.85
+	Hs
		242289 REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13
+	Dm
		52889 Q9W1J5_DROME (50-182): 4.19e-37: 131: 25.37		A1Z823_DROME (22-181): 2.02e-40: 137: 32.50
+	Sc
		863729 YOP1_YEAST (11-178): 1.99e-42: 142: 33.92		PRA1_YEAST (16-179): 9.48e-35: 122: 25.30