HitPredict

Interactor 1: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	25332235, 25900982, 27861801, 33961781, 36199071, 20797629, 11850407
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 605
+	Hs
		962445 HNRPU_HUMAN (1-825): 0: 827: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1312970 HNRL1_HUMAN (6-686): 0: 612: 45.76		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1092945 HNRL2_HUMAN (6-730): 0: 550: 41.98		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1312962 HNRL1_HUMAN (6-686): 0: 612: 45.76		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1092935 HNRL2_HUMAN (6-730): 0: 550: 41.98		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		903135 HNRPU_HUMAN (1-825): 0: 827: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		962230 HNRPU_HUMAN (1-825): 0: 827: 100.00		POC1B_HUMAN (189-438): 4.67e-35: 140: 13.27
+	Hs
		1281357 HNRL1_HUMAN (6-686): 0: 612: 45.76		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1266155 DDX1_HUMAN (257-619): 2.11e-84: 286: 21.41		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		903267 HNRL2_HUMAN (6-730): 0: 550: 41.98		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1345867 MDN1_HUMAN (45-310): 1.77e-32: 138: 17.91		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1266095 DDX1_HUMAN (257-619): 2.11e-84: 286: 21.41		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1281450 ASH2L_HUMAN (157-486): 4.34e-49: 185: 19.29		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Sc
		630897 MDN1_YEAST (36-296): 3.38e-34: 144: 16.73		NLE1_YEAST (223-580): 1.69e-77: 256: 18.81
+	Hs
		1202784 ASH2L_HUMAN (157-486): 4.34e-49: 185: 19.29		WDR5B_HUMAN (409-604): 7.04e-48: 172: 29.27
+	Hs
		903577 ASH2L_HUMAN (157-486): 4.34e-49: 185: 19.29		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1345855 MDN1_HUMAN (45-310): 1.77e-32: 138: 17.91		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21