HitPredict

Interactor 1: NMDE2 (Q00960)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Interactor 2: LIN7B (Q9Z252)
Protein lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2)
Gene: LIN7B

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	10341223
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse GO:0098839 - postsynaptic density membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1482 Rn			1 207
+	Mm
		292486 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		LIN7C_MOUSE (1-196): 1.06e-56: 179: 85.71
+	Hs
		1028152 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		LIN7B_HUMAN (1-207): 5.27e-61: 191: 98.55
+	Hs
		158278 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		LIN7A_HUMAN (5-194): 6.87e-53: 171: 80.00
+	Rn
		962666 NMDE2_RAT (1-1482): 0: 1852: 100.00		DLG2_RAT (24-202): 4.08e-25: 104: 21.74
+	Rn
		677781 NMDE2_RAT (1-1482): 0: 1852: 100.00		DLG4_RAT (24-204): 3.39e-23: 98.3: 21.51
+	Mm
		963769 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		DLG2_MOUSE (24-202): 4.16e-25: 104: 21.74
+	Rn
		962663 NMDE2_RAT (1-1482): 0: 1852: 100.00		DLG1_RAT (67-191): 9.41e-23: 97.4: 28.46
+	Mm
		963732 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		DLG4_MOUSE (24-204): 1.22e-23: 99.9: 21.51
+	Rn
		962664 NMDE2_RAT (1-1482): 0: 1852: 100.00		DLG3_RAT (59-164): 7.05e-21: 91.8: 31.53
+	Mm
		963751 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		DLG1_MOUSE (67-191): 1.34e-22: 96.6: 30.53
+	Mm
		936175 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		DLG3_MOUSE (59-164): 7.62e-21: 91.8: 31.53
+	Hs
		1028140 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		DLG2_HUMAN (24-202): 4.73e-25: 103: 21.74
+	Hs
		1021485 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		DLG1_HUMAN (60-181): 2.57e-23: 99: 30.71
+	Hs
		942337 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		DLG4_HUMAN (24-204): 3.45e-23: 98.3: 21.51
+	Mm
		963735 NMDE2_MOUSE (1-1482): 0: 1846: 99.46		INADL_MOUSE (90-174): 6.64e-15: 74.7: 33.33
+	Hs
		1028145 NMDE2_HUMAN (1-1482): 0: 1828: 98.38		DLG3_HUMAN (93-164): 4.38e-19: 86.8: 38.96
+	Mm
		723533 NMDE1_MOUSE (9-1482): 0: 1507: 52.51		DLG4_MOUSE (24-204): 1.22e-23: 99.9: 21.51
+	Rn
		677780 NMDE1_RAT (9-1482): 0: 1498: 52.31		DLG4_RAT (24-204): 3.39e-23: 98.3: 21.51
+	Mm
		723534 NMDE1_MOUSE (9-1482): 0: 1507: 52.51		INADL_MOUSE (90-174): 6.64e-15: 74.7: 33.33
+	Rn
		291500 NMDE1_RAT (9-1482): 0: 1498: 52.31		MAGI2_RAT (43-202): 1e-13: 71.3: 14.72