HitPredict

Interactor 1: NMDE3 (Q00961)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: Grin2c

Interactor 2: DLG3 (Q62936)
Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)
Gene: DLG3

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16606616
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1237 Rn			1 849
+	Hs
		1060478 NMDE3_HUMAN (1-1237): 0: 1358: 87.70		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Mm
		963785 NMDE3_MOUSE (1-1237): 0: 1418: 96.93		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Rn
		677782 NMDE3_RAT (1-1237): 0: 1411: 100.00		DLG4_RAT (100-849): 0: 572: 62.82
+	Hs
		1021492 NMDE3_HUMAN (1-1237): 0: 1358: 87.70		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Hs
		942343 NMDE3_HUMAN (1-1237): 0: 1358: 87.70		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Rn
		962664 NMDE2_RAT (9-925): 0: 827: 54.30		DLG3_RAT (1-849): 0: 707: 100.00
+	Mm
		936175 NMDE2_MOUSE (9-925): 0: 822: 54.19		DLG3_MOUSE (1-849): 0: 707: 99.65
+	Hs
		1028145 NMDE2_HUMAN (9-925): 0: 829: 54.52		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Rn
		962656 NMDE1_RAT (4-922): 0: 785: 54.90		DLG3_RAT (1-849): 0: 707: 100.00
+	Hs
		1021485 NMDE2_HUMAN (9-925): 0: 829: 54.52		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Mm
		963751 NMDE2_MOUSE (9-925): 0: 822: 54.19		DLG1_MOUSE (4-849): 0: 584: 62.49
+	Hs
		942337 NMDE2_HUMAN (9-925): 0: 829: 54.52		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Rn
		677781 NMDE2_RAT (9-925): 0: 827: 54.30		DLG4_RAT (100-849): 0: 572: 62.82
+	Rn
		962663 NMDE2_RAT (9-925): 0: 827: 54.30		DLG1_RAT (4-849): 0: 570: 60.38
+	Mm
		963732 NMDE2_MOUSE (9-925): 0: 822: 54.19		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Rn
		677780 NMDE1_RAT (4-922): 0: 785: 54.90		DLG4_RAT (100-849): 0: 572: 62.82
+	Rn
		962655 NMDE1_RAT (4-922): 0: 785: 54.90		DLG1_RAT (4-849): 0: 570: 60.38
+	Hs
		1028140 NMDE2_HUMAN (9-925): 0: 829: 54.52		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88
+	Rn
		962666 NMDE2_RAT (9-925): 0: 827: 54.30		DLG2_RAT (315-691): 6.7e-22: 103: 17.83
+	Mm
		963769 NMDE2_MOUSE (9-925): 0: 822: 54.19		DLG2_MOUSE (315-691): 3.19e-22: 104: 17.83