HitPredict

Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: GNL3 (Q9BVP2)
Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
Gene: GNL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	18426907, 21132010, 19033382, 24769896
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 491 Hs			1 549
+	Hs
		962992 MDM2_HUMAN (1-491): 0: 710: 100.00		GNL3L_HUMAN (14-460): 1.33e-130: 394: 35.51
+	Hs
		962774 MDM2_HUMAN (1-491): 0: 710: 100.00		NOG2_HUMAN (8-492): 4.75e-113: 354: 24.80