Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: AATF (Q9NY61)
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1)
Gene: AATF

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.55 0.576

The method score is based on:

Property Details
Experiments 17468107, 25210797
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 0

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Last updated: 15 Jul 2024