HitPredict - High confidence protein-protein interactions

Interactor 1: ESMC (Q01070)
Enhancer of split mgamma protein (E(spl)mgamma) (Split locus enhancer protein mB)
Gene: E(spl)mgamma-HLH

Interactor 2: ESMC (Q01070)
Enhancer of split mgamma protein (E(spl)mgamma) (Split locus enhancer protein mB)
Gene: E(spl)mgamma-HLH

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	9371806
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000987 - cis-regulatory region sequence-specific DNA binding GO:0002052 - positive regulation of neuroblast proliferation and 15 others more... GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0007219 - Notch signaling pathway GO:0007399 - nervous system development GO:0009952 - anterior/posterior pattern specification GO:0030154 - cell differentiation GO:0043565 - sequence-specific DNA binding GO:0046983 - protein dimerization activity GO:0048190 - wing disc dorsal/ventral pattern formation GO:0050767 - regulation of neurogenesis GO:0097150 - neuronal stem cell population maintenance GO:0140297 - DNA-binding transcription factor binding GO:1902692 - regulation of neuroblast proliferation GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1	205
Dm

1	205

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Last updated: 15 Jul 2024