HitPredict - High confidence protein-protein interactions

Interactor 1: RPA49 (Q01080)
DNA-directed RNA polymerase I subunit RPA49 (A49) (DNA-directed RNA polymerase I 49 kDa polypeptide)
Gene: RPA49

Interactor 2: RPA49 (Q01080)
DNA-directed RNA polymerase I subunit RPA49 (A49) (DNA-directed RNA polymerase I 49 kDa polypeptide)
Gene: RPA49

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.90	0.796

Property	Details
Experiments	22615397, 14759368, 18467557
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RNA_pol_I_A49~RNA_pol_I_A49
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0001188 - RNA polymerase I preinitiation complex assembly GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005730 - nucleolus and 8 others more... GO:0005736 - RNA polymerase I complex GO:0006360 - transcription by RNA polymerase I GO:0006361 - transcription initiation at RNA polymerase I promoter GO:0006362 - transcription elongation by RNA polymerase I GO:0006363 - termination of RNA polymerase I transcription GO:0008361 - regulation of cell size GO:0042254 - ribosome biogenesis GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I
Homologous interactions	0

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Last updated: 15 Jul 2024