Interactor 1: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1

Interactor 2: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 9799243, 8816452, 21988832, 18559666
Identification Methods pull down, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~zf-CCCH
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0016607 - nuclear speck
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 240
Hs

1 248
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024