Interactor 1: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1

Interactor 2: U2AF4 (Q8WU68)
Splicing factor U2AF 26 kDa subunit (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4) (U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3) (U2 small nuclear RNA auxiliary factor 1-like protein 3) (U2AF1-like protein 3)
Gene: U2AF1L4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~zf-CCCH, zf-CCCH~zf-CCCH
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0016607 - nuclear speck
GO:0030628 - pre-mRNA 3'-splice site binding
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 240
Hs

1 220
+ At
+ At
+ At
+ Sp
+ Hs
+ Hs

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Last updated: 15 Jul 2024