HitPredict

Interactor 1: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 28514442, 33961781, 22365833, 23602568
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0016607 - nuclear speck
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 240
Hs

1 655
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024