HitPredict

Interactor 1: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005516 - calmodulin binding GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2364 Hs			1 656
+	Hs
		1068620 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		967163 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		967188 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		318620 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		726832 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35