HitPredict

Interactor 1: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0003779 - actin binding GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2364 Hs			1 1124
+	Hs
		1329040 SPTN4_HUMAN (5-2092): 2.42e-155: 540: 52.21		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		211670 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		993298 ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (1359-2356): 5.1e-25: 117: 13.42		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		974153 DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		513898 DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1045536 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1068674 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343798 MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		164668 SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		527106 SPTCA_DROME (288-1964): 1.34e-160: 555: 18.16		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84