HitPredict

Interactor 1: TIAR (Q01085)
Nucleolysin TIAR (TIA-1-related protein)
Gene: TIAL1

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 383
+	Hs
		125430 PABP4_HUMAN (2-288): 4.71e-64: 217: 24.15		WWP2_HUMAN (45-319): 1.29e-33: 134: 15.85
+	Hs
		1031480 PABP4_HUMAN (2-288): 4.71e-64: 217: 24.15		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		516643 PABP1_HUMAN (195-285): 4.67e-12: 69.4: 25.77		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Hs
		125122 PABP1_HUMAN (195-285): 4.67e-12: 69.4: 25.77		WWP2_HUMAN (45-319): 1.29e-33: 134: 15.85
+	Hs
		516721 PABP1_HUMAN (195-285): 4.67e-12: 69.4: 25.77		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		1329986 PABP3_HUMAN (195-285): 3.7e-11: 66.7: 24.74		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87