HitPredict

Interactor 1: NMDE2 (Q01097)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0035255 - ionotropic glutamate receptor binding GO:0044877 - protein-containing complex binding GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1482 Mm			1 1186
+	Mm
		723527 NMDE1_MOUSE (9-1482): 0: 1530: 52.84		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		919690 NMDE2_MOUSE (1-1482): 0: 1874: 100.00		RAP1A_MOUSE (398-567): 1.81e-70: 235: 23.03
+	Mm
		620886 GRIA1_MOUSE (12-901): 0: 683: 20.04		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		723576 NMDZ1_MOUSE (14-940): 0: 681: 23.41		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Rn
		585155 GRIA1_RAT (12-901): 0: 685: 20.04		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Mm
		620948 GRIA2_MOUSE (8-871): 0: 674: 21.16		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Rn
		585178 GRIA2_RAT (8-871): 0: 675: 21.16		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Mm
		100188 F6YNQ1_MOUSE (81-901): 0: 644: 20.74		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Hs
		786742 GRIA2_HUMAN (8-871): 0: 677: 21.16		AGAP2_HUMAN (1-1147): 0: 987: 94.10
+	Mm
		723556 NMDZ1_MOUSE (14-940): 0: 681: 23.41		RAP1A_MOUSE (398-567): 1.81e-70: 235: 23.03