HitPredict

Interactor 1: NMDE3 (Q01098)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: Grin2c

Interactor 2: EPS8 (Q08509)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17018287
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0017146 - NMDA selective glutamate receptor complex GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1239 Mm			1 821
+	Mm
		723526 NMDE1_MOUSE (3-954): 0: 771: 53.58		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		620884 GRIA1_MOUSE (7-870): 0: 674: 21.87		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Mm
		723575 NMDZ1_MOUSE (9-933): 0: 644: 23.72		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Hs
		412171 NMDE2_HUMAN (9-943): 0: 819: 52.81		FYN_HUMAN (455-593): 1.72e-30: 128: 16.31
+	Hs
		412157 NMDE1_HUMAN (4-954): 0: 758: 53.80		FYN_HUMAN (455-593): 1.72e-30: 128: 16.31
+	Hs
		178302 NMDE4_HUMAN (30-866): 0: 660: 62.99		CRK_HUMAN (394-701): 8.81e-39: 148: 11.00
+	Hs
		412144 NMDZ1_HUMAN (9-933): 0: 644: 23.72		FYN_HUMAN (455-593): 1.72e-30: 128: 16.31